We study how mutations in epigenetic regulators lead to wide-ranging defects in gene regulation and the development of blood and other malignancies.
Mar 27th, 2017
CRISPR-Cas9–guided oncogenic chromosomal translocations with conditional fusion protein expression in human mesenchymal cells
Mar 22nd, 2017
Neri F et al., Intragenic DNA methylation prevents spurious transcription initiation. Nature, 2017.
Mar 14th, 2017
“Transcription control by the ENL YEATS domain in acute leukaemia”, Erb et al, Nature 2017