Welcome to the Licht Lab!

We study how mutations in epigenetic regulators lead to wide-ranging defects in gene regulation and the development of blood and other malignancies.


Journal club 3/27

CRISPR-Cas9–guided oncogenic chromosomal translocations with conditional fusion protein expression in human mesenchymal cells

Journal Club 3/21

Neri F et al., Intragenic DNA methylation prevents spurious transcription initiation. Nature, 2017.

Journal Club 3/14

“Transcription control by the ENL YEATS domain in acute leukaemia”, Erb et al, Nature 2017