Journal club: 2017 Schedule Date Presenter Paper 11/21 Kartika Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia 11/16 Xiaoxiao RNA targeting with CRISPR–Cas13 10/9 Camille MELK is not necessary for the proliferation of basal-like breast cancer cells 8/7 Xiaoxiao JMJD-5/KDM8 regulates H3K36me2 and is required for late steps of homologous recombination and genome integrity 8/3 Camille Wolf–Hirschhorn Syndrome Candidate 1 (whsc1) Functions as a Tumor Suppressor by Governing Cell Differentiation 7/19 Rich Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras 7/11 Daphne Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation 7/5 Marta Genome-wide characterization of mammalian promoters with distal enhancer functions 6/7 Sayantan The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells 5/30 Kartika CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression 5/16 Xiaoxiao PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining 5/11 Catalina Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia 5/2 Rich Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial–mesenchymal transition
