2019 Publications


Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding

Huang X, LeDuc RD, Fornelli L, Schunter AJ, Bennett RL, Kelleher NL, Licht JD.

J Biol chem, 294 (33), pp. 12459-12471, 2019.
10.1074/jbc.RA118.006159
https://www.ncbi.nlm.nih.gov/pubmed/31248990



A Mutation in Histone H2B Represents a New Class of Oncogenic Driver

Bennett RL, Bele A, Small EC, Will CM, Nabet B, Oyer JA, Huang X, Ghosh RP, Grzybowski AT, Yu T, Zhang Q, Riva A, Lele TP, Schatz GC, Kelleher NL, Ruthenburg AJ, Liphardt J, Licht JD.

Cancer Discovery, 9 (10), pp. 1438-1451, 2019.
10.1158/2159-8290
https://cancerdiscovery.aacrjournals.org/content/9/10/1438.long